This Act prohibits federal funding and solicitation of human fetal tissue obtained through induced abortions while permitting research using tissue from miscarriages or stillbirths under revised regulations.
Cindy Hyde-Smith
Senator
MS
The Protecting Life and Integrity in Research Act of 2025 prohibits all federal funding and support for research utilizing human fetal tissue obtained as a result of an induced abortion. The bill restricts federal agencies to only conducting or supporting research using tissue obtained after a miscarriage or stillbirth, subject to new regulations. Furthermore, it makes it illegal for individuals to solicit or knowingly accept donations of human fetal tissue obtained pursuant to an induced abortion.
The Protecting Life and Integrity in Research Act of 2025 is a major policy shift that hits the scientific community squarely in the research lab. Simply put, this bill slams the door shut on federal funding and support for any research that uses human fetal tissue obtained as a result of an induced abortion. This is a hard stop, affecting every federal department, agency, and office, fundamentally changing how certain medical research is conducted in the U.S.
Section 2 of the bill creates a massive firewall: if a study relies on tissue derived from an induced abortion, the National Institutes of Health (NIH) or any other federal body cannot fund it, approve it, or even conduct it themselves. This isn’t a suggestion; it’s a total ban on federal involvement with that specific source material. For scientists working on genetic therapies, vaccine development, or understanding complex diseases like HIV—fields that have historically relied on these specific cell lines—this means a significant, immediate halt to current projects and a scramble to find alternative, ethically compliant sources.
Beyond funding, the bill makes it illegal for researchers or institutions to knowingly ask for, receive, or accept a donation of human fetal tissue if they know it came from an induced abortion. This prohibition, detailed in Section 3, puts the onus on the recipient to ensure the tissue's provenance. While the intent is clear—to eliminate the market for this tissue—the practical effect is adding a layer of legal risk for any institution involved in tissue transfer. If you’re running a lab that relies on tissue banks, you now have a new, stringent legal compliance hurdle to clear, backed by the threat of penalties if you fail to prove you didn't 'knowingly' acquire prohibited tissue.
It’s important to note what remains permitted. Federal agencies can still support research using human fetal tissue obtained after a miscarriage or a stillbirth. However, even this permissible research is now subject to stricter rules under the revised Public Health Service Act (PHSA). For example, if that tissue is intended for transplantation, new regulations dictate how the donation must be handled before the transfer takes place. The bill also explicitly allows federal agencies to develop new, ethical cell lines and genetic tools, provided those lines are not derived from induced abortion tissue. This is the bill’s attempt to steer research toward alternative pathways, but developing viable substitutes for established cell lines can take years and significant funding.
For the average person, this bill might seem abstract, but it touches directly on the speed and scope of medical innovation. Consider the development of the polio vaccine, which relied heavily on fetal tissue research. By eliminating a key source material, this bill potentially slows down research into complex areas like neurological disorders or cancer treatments that require specific human developmental models. The negatively impacted groups here are the medical researchers who lose a critical tool, and potentially the patients who might have benefited from the breakthroughs that now face delays. The bill prioritizes an ethical stance on the source material over the potential pace of scientific discovery, forcing researchers to quickly pivot or risk losing federal support entirely.