PolicyBrief
H.R. 6089
119th CongressNov 18th 2025
Biomanufacturing Excellence Act of 2025
IN COMMITTEE

This Act establishes the National Biopharmaceutical Center of Excellence to advance domestic biomanufacturing science, scale production, and strengthen the national supply chain and workforce.

Chrissy Houlahan
D

Chrissy Houlahan

Representative

PA-6

LEGISLATION

New Biomanufacturing Center Gets $120M to Cut Drug Supply Chain Headaches and Boost US Jobs

The Biomanufacturing Excellence Act of 2025 is all about bringing the future of medicine and materials production back home. This bill establishes the National Biopharmaceutical Manufacturing Center of Excellence under the National Institute of Standards and Technology (NIST). Think of it as a federally funded, high-tech factory and training hub rolled into one, designed to solve the biggest problems in making complex drugs and biological products in the U.S.

The $120 Million Fix for Supply Chains

This isn't about building another government office. The core of this legislation is Section 3, which authorizes $120,000,000 for fiscal year 2026 to fund the creation and operation of this Center. NIST must award a competitive grant or agreement to a non-federal entity—like a university consortium or a public-private partnership—within 180 days of the bill’s enactment. The main goal? To reduce our reliance on foreign supply chains for critical medicines and materials, which Congress specifically notes is a vulnerability to our national, health, and economic security (Sec. 2).

If you’ve ever worried about drug shortages or seen the price of a critical medicine spike, this Center aims to tackle the root cause: the difficulty and expense of scaling up new biopharma production here in the U.S. The Center will focus on developing and demonstrating flexible manufacturing technologies and systems, essentially figuring out how to make new drugs faster and cheaper at a commercial scale, thereby reducing supply bottlenecks (Sec. 3).

From Lab Bench to Assembly Line: What It Means for Innovation

For researchers and startups in the biotech space, this Center is a huge deal. The bill recognizes that the biggest obstacle for U.S. manufacturers is proving that their innovative processes can actually generate a profit and scale up (Sec. 2). The Center will provide the infrastructure and collaborative research space needed to bridge that gap. For example, a small biotech firm that has developed a revolutionary new cell therapy might partner with the Center to test and standardize its production process, ensuring it meets strict Good Manufacturing Practices (GMPs) before it hits the market.

This focus on standardization—called quality by design—is key. By clarifying the manufacturing controls and methods, the Center aims to make it easier for regulatory agencies to approve innovative new production techniques, speeding up the transition from discovery to patient access (Sec. 3).

The Workforce Angle: Your Next Career Move

One of the most practical aspects of this bill is the heavy emphasis on workforce development. The Center is explicitly required to partner with educational and community organizations to build the biotechnology talent pool (Sec. 3). This means new training programs, certifications, and apprenticeships will be popping up in the areas surrounding the selected Center.

If you’re a recent grad, a veteran transitioning to civilian life, or a manufacturing worker looking to upskill, this Center is designed to create a pipeline for highly skilled, well-paying jobs in biomanufacturing. The goal is to ensure the U.S. has the talent ready to operate the complex tools and equipment needed to keep these high-tech factories running.

The Fine Print: Who’s Making the Call?

While the objectives are clearly beneficial—secure supply chains, faster drug development, and better jobs—the selection process for the single entity that gets to run this Center is where the regulatory rubber meets the road. NIST must evaluate applicants based on criteria like their past performance, proximity to existing biomanufacturing infrastructure, and co-investment from private sources.

However, the selection criteria also include a catch-all: “Any other criteria the Director deems relevant” (Sec. 3). This gives the Director significant, undefined discretion when choosing the winner of this massive grant. For taxpayers, this means we’re trusting the Director to use that broad authority wisely to select the entity that will truly deliver on the promise of domestic excellence, rather than one that just looks good on paper. The bill attempts to mitigate this by requiring the Director to submit annual public reports on the Center’s progress, activities, and findings, ensuring transparency and accountability for that $120 million investment over time.